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The effect of quercetin on the human body(1)

1. Quercetin and Respiratory Health

Quercetin has good expectorant and antitussive effects, and has a certain antiasthmatic effect. It has been used for a long time in the treatment of chronic bronchitis. The effects of quercetin on respiratory health are achieved through multiple pathways including mucus secretion, anti-viral, anti-fibrotic, and anti-inflammatory.

Quercetin also has a wide range of anti-fibrotic effects, including anti-liver, lung, heart and kidney fibrosis, and its mechanism of action is complex, including inhibition of fibroblast proliferation, inhibition of collagen synthesis, prevention of oxidative damage, inhibition of angiogenesis, etc. .


2. Antioxidant function of quercetin

Free radicals are normal metabolites in the body. When the free radicals in the body are excessive and unbalanced, it may lead to aging, inflammation, cancer, cardiovascular and cerebrovascular diseases, etc. Experiments show that flavonoids have good scavenging effects on free radicals and superoxide anions.

The antioxidant activity of quercetin protects the mucosal system in the following ways.

①Quercetin prevents lipid oxidation, and it is important to protect the lipid bilayer of the cell walls of the gastrointestinal tract, as these cells are an important part of the body's immune system;

②Quercetin may protect liver cells against alcohol-induced oxidative damage by reducing glutathione consumption, increasing antioxidant enzyme activity, and inhibiting lipid peroxidation. The protective effect is in a dose-time effect relationship.

③Quercetin increases the mucus secretion of gastric cells, and the mucopolysaccharide forms a buffer layer on the gastric mucosa, reducing the contact between gastric acid and the gastric wall.

Studies have found that supplementing quercetin with feed can not only significantly improve the antioxidant capacity of peripheral blood of animals, but also save and protect vitamin C and vitamin E. It indicated that quercetin could directly or indirectly exert antioxidant effect in vivo after intestinal absorption.