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The effect of quercetin on the human body(2)

3. Anti-inflammatory effect

Quercetin reduces the body's immune response to allergens, inhibits IgE-mediated release of allergic mediators from mast cells and IgG-mediated histamine release.

Quercetin is a potent inhibitor of lipoxygenase, reducing the production of pro-inflammatory arachidonic acid metabolites. In addition, quercetin can reduce the entry of highly antigenic proteins, antigens, and allergenic microorganisms into the body.

Neutrophils are the most important inflammatory cells in the body's early inflammatory response, and they play a central role in the inflammatory response.

Quercetin has no obvious effect on spontaneous apoptosis of neutrophils, but it can inhibit the delay of spontaneous apoptosis of neutrophils caused by the inflammatory factor LPS. At the same time, quercetin also reduces the sensitivity of neutrophils to inflammatory factors, so as to achieve the purpose of anti-inflammatory.


4. Antibacterial effect

Qin Xiaorong et al. used Escherichia coli and Staphylococcus aureus as experimental strains, and the results showed that quercetin had the best antibacterial effect on Staphylococcus aureus. The antibacterial effect on Bacillus colloids is second; it also has obvious antibacterial effect on Escherichia coli, Bacillus thuringiensis, Bacillus subtilis, and Pseudomonas aeruginosa; it has no antibacterial effect on Bacillus hominis. Quercetin has broad-spectrum antibacterial activity, and its antibacterial effect on Gram-negative bacteria is stronger than that of Gram-positive bacteria.