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Luteolin as a regulator of skin aging and inflammation

Luteolin plays an important role in resisting ultraviolet radiation by partially absorbing UVA and UVB radiation. Therefore, luteolin can also act as the first line of defense to reduce adverse photobiological effects in the skin.

Luteolin has good anti-inflammatory and antioxidant activities, can inhibit inflammatory mediators, and regulate a variety of skin inflammation. Luteolin is widely used in skin aging and skin cancer, wound healing and inflammatory skin diseases (including psoriasis, contact dermatitis and atopic dermatitis).

Unique properties of luteolin

Luteolin acts as a natural antihistamine by preventing mast cells from degranulation; It works by inhibiting γ- Aminobutyric acid A (GABAA) receptor to reduce airway mucus production; It reduces inflammation by regulating immune cytokines; It can cross the blood brain barrier.

The discovery of its unique molecular mechanism of action has made luteolin the focus of attention as a potential therapy for allergy, asthma, eczema and even neuroinflammation.