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Dihydroquercetin is a polyphenol widely found in plants. It is not only widely distributed in nature, but also has a variety of biological activities, especially in anti-oxidation. Studies have shown that dihydroquercetin can enhance the activity of the intracellular antioxidant system through a variety of mechanisms, effectively scavenge free radicals, and reduce the damage of oxidative stress to cells.

First, dihydroquercetin can directly remove free radicals. Free radicals are the main products of oxidative stress. They are highly reactive and unstable, and can react with macromolecules in cells, causing damage to cell structure and function.

Dihydroquercetin has multiple phenolic hydroxyl groups, which can undergo redox reactions with free radicals and convert them into stable compounds, thereby effectively removing free radicals and reducing the damage to cells caused by oxidative stress.

Secondly, dihydroquercetin can upregulate the activity of antioxidant enzymes. Antioxidant enzymes are a class of enzymes that can catalyze redox reactions. They reduce the damage of oxidative stress to cells by catalyzing the decomposition of harmful substances such as hydrogen peroxide and superoxide anions.

In addition, dihydroquercetin can also enhance the activity of the antioxidant system by regulating cell signaling pathways.

Multiple signaling pathways in cells are involved in the regulation of antioxidant stress, such as the Nrf2-Keap1 signaling pathway and the MAPK signaling pathway. The activation or inhibition of these signaling pathways can affect the expression and function of antioxidant enzymes, thereby affecting the antioxidant capacity of cells.

In summary, dihydroquercetin, as a natural compound with significant antioxidant activity, plays an important role in enhancing the activity of the intracellular antioxidant system.